Northern California is the epicenter of the cannabis world and it is also the home of the Emerald Cup, the world’s largest running outdoor cannabis competition. The 11th annual Emerald Cup will be held on December 14th and 15th at the Sonoma County Fairgrounds in Santa Rosa, CA. SC Laboratories will be sponsoring this event as well as providing lab testing on all entries. In addition to awards for the best flowers there will also be awards presented for best edible, topical, solventless extract, and as well as a breeders cup.
The event features two days of incredible music, world renowned speakers, hands on workshops, and hundreds of vendors with something for every cannabis enthusiast. Check out the Emerald Cup's website for more information here: http://theemeraldcup.com/
HempCon is a medical cannabis event catering to anyone who might benefit from the use of cannabis. The San Bernardino HempCon will take place October 17-19, 2014 at the National Orange Show Event Center. SC Laboratories will be sponsoring this event as well as providing lab testing for the cannabis cup with awards going to the best indica, sativa, hybrid, CBD, and edible product.
This event will also feature over two hundred cannabis exhibitors including dispensaries, collectives, caregivers, on site medical marijuana evaluations, and state of the art glass and grow products. There will also be seminars led by industry leaders, advocates, and attorneys.
Learn more at http://hempcon.com/
Located in the heart of California, the Santa Cruz region is extremely cannabis centric. Santa Cruz County is home to ideal weather conditions for marijuana cultivation and the cannabis hub for the western United States. Which is why once a year we hold the Santa Cruz Cup for Medicinal Cannabis to enjoy, discuss, and celebrate the best medicine on the west coast.
This years event will be held at a very spacious 500+ capacity venue. Featuring an outdoor festival with booths from local businesses, educational exhibits, Santa Cruz Cup collectives and an indoor Music Concert / Awards Ceremony
Secure Santa Cruz Location
November 16th, 2014:
2pm Doors open
2-9pm Music, Exhibits, Games, etc..
9:30pm Awards Ceremony
10pm Raffle Awards
What are migraines?
Throbbing, pulsating, and excruciatingly painful, migraine headaches can be debilitating and affect over 23 million people in the US alone. Migraine headaches are recurrent headaches that typically affect one side of the head and are often accompanied by nausea. Migraines induce a state of hyperalgesia in a patient causing sensitivity to stimuli that would not normally cause pain. Though some pieces of the puzzle have been assembled, a complete picture of why migraine headaches occur has not yet been fully elucidated. However, what has been determined by researchers is the areas from which this pain arises, some of the molecular changes that occur during a migraine, and how cannabinoids can modify these changes.
What happens during a migraine?
Prior to a migraine attack, levels of the neurotransmitter serotonin are substantially increased and subsequently, during the headache that follows these levels drop to below normal. During a migraine neurons in the trigeminal ganglia also release neuropeptides called Substance P, Neurokinin A, and calcitonin gene-related peptide (CGRP). The release of these neuropeptides leads to vasodilation and an increase in pro-inflammatory molecules in the surrounding area leading to irritation of the nerve and hyperalgesia (increased sensitivity).
How can cannabis prevent migraine headaches?
As previously mentioned, alterations in serotonin levels have been linked to migraines and it has been shown that there is some interplay that occurs between cannabinoids and the serotonergic system. These alterations arise from the release of serotonin from platelets causing a spike of serotonin in the blood. This spiking is the first step in the generation of a migraine. Cannabis can be used as a prophylactic in these scenarios because it has been shown to prevent this release of serotonin from blood platelets . In addition, THC has also been shown to increase serotonin synthesis, which could also help mitigate the deficits from migraine depletion .
How does cannabis alleviate migraine symptoms?
Cannabis has long history of use for relief from pain and nausea and our own endocannabinoids also have an influence on these states. This led researchers to believe that migraines could be classified as a clinical endocannbinoid deficiency (CECD). The support for this idea comes from the observation that body’s endogenous cannabinoid anandamide along with other cannabinoid receptor partial agonists, like THC, augment serotonin release and the way the serotonergic system relays pain information . For example, anandamide has been shown to produce an inhibitory effect on a subtype of serotonin receptor called 5-HT3 . This receptor is a mediator of emesis (vomiting) and pain responses, which could partially explain how cannabis can alleviate the pain and nausea associated with migraines.
Cannabinoids also have an effect on the areas that are thought to generate this pain. In the trigeminal nerve, cannabinoids have been shown to quell inflammation and produce analgesia . Further research on this area of the brain using synthetic cannabinoid agonists has shown that CB1 receptor activation actually reduces the amount of pain signals produced from this region . Many studies have also consistently cited an area of the brain called the periaqueductal gray matter (PAG) in the generation of migraines . Studies on this area of the brain using synthetic cannabinoid agonists (compounds similar to THC) have shown reduced responses to pain .
Researchers have concluded that cannabinoids interact with the serotonergic system and the trigeminal nerve to provide preventative benefits as well as relief from migraine symptoms. Though much progress has been made in understanding the mechanisms of migraines and how cannabinoids augment them, to date there have been little to no human studies performed to fully confirm these findings. However, regardless of a lack of clinical studies there is a mountain of anecdotal evidence and preclinical data to support the use of cannabis for migraine prevention and treatment.
SC Laboratories President Josh Wurzer will be giving two presentations at the conference on Wednesday. His first presentation will cover the basics of the cannabinoids, the body’s endocannabinoid system, and the therapeutic potential of the endocannabinoid system in a variety of ailments. His second presentation will cover the importance of laboratory testing and the methods involved in screening cannabis for potency, pesticides, residual solvents, and terpene content.
The Marijuana for Medical Purposes Conference organized by the International Pharmaceutical Academy, will be held September 16–17, 2014 in Toronto, Canada. This conference will assemble the top minds in medical marijuana to discuss every aspect of the industry. Participants of the conference will gain valuable knowledge of the best global practices for the business, technology, science, research, laws and regulations of medical marijuana in Canada. Established and outdated mindsets regarding cannabinoids will be challenged with up to date knowledge and research, and experts will offer a forecast of the next 3–5 years for the industry.
For more info about the Marijuana for Medical Purposes Conference check out their website at the following link: http://www.ipacanada.com/Marihuana_Medical_Purposes_2014/